The computational neuroscience unit at the CRM was founded in 2012 and is made up of three Principal Investigators (Alex Roxin, Klaus Wimmer and Alex Hyafil) and their groups. The unit is an active member of a larger, Barcelona-wide Neuroscience community which includes theoretical, experimental and clinical groups located in a variety of university departments and research centers (www.barccsyn.org). Research in the computational neuroscience unit is largely focused on systems-level neuroscience. Broadly speaking, this involves investigating how large assemblies of interacting neurons give rise to animal and human behavior. Our approach is generally to combine computational modeling with data analysis.